Data completeness
3/8 — Basic
FUROSEMIDE (furosemide) by R-Pharm US is clinical pharmacology investigations into the mode of action of furosemide have utilized micropuncture studies in rats, stop flow experiments in dogs and various clearance studies in both humans and experimental animals. Approved for heart failure, essential hypertension.
Drug data last refreshed 2w ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Furosemide is a loop diuretic that inhibits sodium and chloride reabsorption in the proximal tubule, distal tubule, and loop of Henle, making it highly effective for fluid overload management. It is indicated for heart failure and essential hypertension, with oral tablet formulation offering 64% bioavailability and a 2-hour duration of effect. The drug works as a potent diuretic with rapid onset (within 5 minutes IV, peak effect within 30 minutes) and is extensively protein-bound at therapeutic concentrations.
Pre-Launch
Pre-launch stage indicates a newly developed or repositioned formulation with potential for significant commercial build-out; commercial team will focus on market access, payer negotiations, and field force deployment.
Mechanism of Action
CLINICAL PHARMACOLOGY Investigations into the mode of action of furosemide have utilized micropuncture studies in rats, stop flow experiments in dogs and various clearance studies in both humans and experimental animals. It has been demonstrated that furosemide inhibits primarily the reabsorption…
Worked on FUROSEMIDE at R-Pharm US? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.