NDAINJECTIONINJECTABLE
Approved
Dec 1994
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
7
Data completeness
6/8 — Strong
FRAGMIN (dalteparin sodium) by Pfizer is properties. Approved for non-q-wave myocardial infarction, concurrently administered with aspirin therapy [see ], deep vein thrombosis (dvt) and 2 more indications. First approved in 1994.
Drug data last refreshed 2h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
FRAGMIN (dalteparin sodium) is a low-molecular-weight heparin (LMWH) injectable anticoagulant that works by enhancing Factor Xa and thrombin inhibition through antithrombin. It is indicated for prevention and treatment of deep vein thrombosis (DVT), pulmonary embolism (PE), non-Q-wave myocardial infarction, and venous thromboembolism (VTE) recurrence in pediatric patients.
$0.002BPart D
LOE ApproachingProduct is approaching loss of exclusivity with modest Part D utilization; commercial teams may be restructuring to focus on pipeline or adjacent franchises.
Mechanism of Action
properties. It acts by enhancing the inhibition of Factor Xa and thrombin by antithrombin. In humans, dalteparin potentiates preferentially the inhibition of coagulation Factor Xa, while only slightly affecting the activated partial thromboplastin time (APTT).
Indications (3)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.