FOSFOMYCIN TROMETHAMINE (fosfomycin tromethamine) by Aurobindo Pharma is clinical pharmacology absorption fosfomycin tromethamine is rapidly absorbed following oral administration and converted to the free acid, fosfomycin. Approved for pyelonephritis, perinephric abscess. First approved in 2024.
CLINICAL PHARMACOLOGY Absorption Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to the free acid, fosfomycin. Absolute oral bioavailability under fasting conditions is 37%. After a single 3-gram dose of fosfomycin tromethamine, the mean (± 1 SD) maximum…
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PK/PD and Safety/Tolerability of Two Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adults
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