NDAORALTABLET
Approved
Apr 2005
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
11
Mechanism of Action
action. At the cellular level, alendronate shows preferential localization to sites of bone resorption, specifically under osteoclasts. The osteoclasts adhere normally to the bone surface but lack the ruffled border that is indicative of active resorption. Alendronate does not interfere with…
Pharmacologic Class:
Vitamin D
Indications (1)
Clinical Trials (5)
A Study to Evaluate the Drug-Drug Interaction Between Enlicitide Decanoate (MK-0616) and Alendronate in Healthy Adult Participants (MK-0616-027)
Started Apr 2024
36 enrolled
Healthy
Alendronate in Juvenile Osteoporosis
Started Jul 2009
11 enrolled
Juvenile OsteoporosisLow Bone DensityFractures
Secondary Prevention of Osteoporosis
Started Feb 2007
29 enrolled
Osteoporosis
The Effects of Alendronate After Cure of Primary Hyperparathyroidism
Started Jul 2006
0Hyperparathyroidism
Upper GI Handling of Branded vs. Generic Alendronate
Started Dec 2005
25 enrolled
Osteoporosis