NDAINJECTIONINJECTABLE
Approved
Jun 1947
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
16
Data completeness
3/8 — Basic
FOLVITE (folic acid) by Pfizer is clinical pharmacology folic acid acts on megaloblastic bone marrow to produce a normoblastic marrow. First approved in 1947.
Drug data last refreshed 20h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
FOLVITE (folic acid) is a water-soluble B vitamin used to treat megaloblastic and macrocytic anemias caused by folic acid deficiency. It works by converting to tetrahydrofolic acid, a critical cofactor in DNA synthesis and nucleoprotein formation, restoring normal erythropoiesis in bone marrow. The injectable formulation enables rapid systemic delivery for patients unable to absorb oral folate or requiring immediate repletion.
LOE Approaching
As a product approaching loss of exclusivity with limited commercial growth trajectory, career opportunities focus on cost optimization, supply chain efficiency, and lifecycle extension rather than field expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Folic acid acts on megaloblastic bone marrow to produce a normoblastic marrow. In man, an exogenous source of folate is required for nucleoprotein synthesis and the maintenance of normal erythropoiesis. Folic acid is the precursor of tetrahydrofolic acid, which is involved as…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.