FLUOCINONIDE
LOE ApproachingNDATOPICALGEL
Approved
May 1973
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
3/8 — Basic
FLUOCINONIDE by Alvogen is clinical pharmacology topical corticosteroids share anti-inflammatory, anti-pruritic and vasoconstrictive actions. First approved in 1973.
Drug data last refreshed 15h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Fluocinonide is a potent topical corticosteroid formulated as a gel that provides anti-inflammatory, anti-pruritic, and vasoconstrictive effects for dermatological conditions. It works by modulating inflammatory pathways, though the exact mechanism remains incompletely understood; absorption is enhanced by skin inflammation, occlusion, and barrier disruption. Patients with inflammatory skin conditions requiring topical steroid therapy are the primary users.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100), suggesting declining team expansion and focus on cost management and generic transition planning.
Mechanism of Action
CLINICAL PHARMACOLOGY Topical corticosteroids share anti-inflammatory, anti-pruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Fluocinonide Cream in Treating Symptoms of Vaginal Dryness and Painful Sexual Intercourse In Patients With Breast Cancer Undergoing Hormone Therapy
Started Sep 2011
34 enrolled
Breast Carcinoma
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.