FLUCONAZOLE by Teva is mechanism of action fluconazole is a highly selective inhibitor of fungal cytochrome p450 dependent enzyme lanosterol 14-α-demethylase. First approved in 2004.
Drug data last refreshed 23h ago
Mechanism of Action Fluconazole is a highly selective inhibitor of fungal cytochrome P450 dependent enzyme lanosterol 14-α-demethylase. This enzyme functions to convert lanosterol to ergosterol. The subsequent loss of normal sterols correlates with the accumulation of 14-α-methyl sterols in fungi…
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis
A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis
A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B
A Study to Compare the Use of Fluconazole as Continuous Therapy Versus Periodic Therapy in HIV-Positive Patients With Recurrent Thrush
A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone
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