NDAORALTABLET1 Generic Approved
Approved
Oct 2011
Lifecycle
Peak
Competitive Pressure
45/100
Clinical Trials
9
Data completeness
5/8 — Partial
FERRIPROX (deferiprone) by Chiesi is iron chelating activity [moa]. Approved for iron chelator [epc]. First approved in 2011.
Drug data last refreshed 19h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
FERRIPROX (deferiprone) is an oral iron chelator approved in 2011 for treating iron overload associated with beta thalassemia major and other iron overload conditions. It works by binding excess iron in the body and facilitating its excretion, reducing iron-related organ damage. The drug represents a key therapeutic option in managing chronic transfusion-dependent anemias.
Peak2.0 years to LOE
FERRIPROX is at peak commercial stage with $4M in spending, positioning it as a solid secondary option in a competitive iron chelation market dominated by Novartis' JADENU franchise.
Mechanism of Action
Iron Chelating Activity
Pharmacologic Class:
Iron Chelator
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (9)
Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload
Started Mar 2019
30 enrolled
Iron Overload Due to Repeated Red Blood Cell Transfusions
Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children
Started Nov 2018
64 enrolled
Beta Thalassemia Major AnemiaIron Overload
Study of Parkinson's Early Stage With Deferiprone
Started Oct 2016
140 enrolled
Parkinson's Disease
Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias
Started May 2015
134 enrolled
Iron OverloadSickle Cell DiseaseOther Anemias
Long-term Deferiprone Treatment in Patients With Pantothenate Kinase-Associated Neurodegeneration
Started Jun 2014
68 enrolled
Pantothenate Kinase-Associated Neurodegeneration
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.