FERAHEME

LOE Approaching

ferumoxytol

NDAINTRAVENOUSSOLUTION
Approved
Jun 2009
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
15

Mechanism of Action

shell, which helps to isolate the bioactive iron from plasma components until the iron-carbohydrate complex enters the reticuloendothelial system macrophages of the liver, spleen and bone marrow. The iron is released from the iron-carbohydrate complex within vesicles in the macrophages. Iron then…

Pharmacologic Class:

Parenteral Iron Replacement

Indications (1)

iron deficiency anemia (IDA) in adult patients: •

Clinical Trials (5)

NCT07400406N/ARecruiting

A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance for the Detection of Calcified Coronary Arteries

Started Jan 2024
NCT06146751N/ARecruiting

A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance Imaging for the Detection of Intracardiac Thrombus

Started Nov 2023
NCT05045872Phase 1Completed

Assessment of Renal Vasculature and Function with Ferumoxytol-enhanced Magnetic Resonance Imaging

Started Sep 2021
NCT02857218Phase 1Withdrawn

Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Stage IIB-IIIC Esophageal Cancer

Started Apr 2018
0
Stage IIB Esophageal Cancer AJCC v7Stage III Esophageal Cancer AJCC v7Stage IIIA Esophageal Cancer AJCC v7+2 more
NCT03280277Phase 1Terminated

Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer

Started Apr 2018
2 enrolled
Locally Advanced Rectal CarcinomaStage III Rectal Cancer AJCC v7Stage IIIA Rectal Cancer AJCC v7+2 more
External Resources
DailyMed
Full prescribing information
FDA Drugs@FDA
FDA approval history
RxNorm
Drug nomenclature & identifiers