FACTREL
LOE ApproachingNDAINJECTIONINJECTABLEPriority Review
Approved
Sep 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
FACTREL by Hikma is mechanism of action follicular cysts are enlarged non-ovulatory follicles resulting from a malfunction of the neuroendocrine mechanism controlling follicular maturation and ovulation. First approved in 1982.
Drug data last refreshed 16h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
FACTREL (gonadorelin) is a small-molecule gonadotropin-releasing hormone (GnRH) agonist administered by injection that induces release of endogenous luteinizing hormone (LH) to treat follicular cysts in cattle by promoting ovulation or cyst regression. The drug works by mimicking the natural neuroendocrine mechanism controlling follicular maturation, effectively inducing ovulation of dominant ovarian follicles during the bovine estrous cycle.
LOE Approaching
Product is nearing loss of exclusivity with moderate competitive pressure (30%), signaling a contracting or stable team focused on brand defense and market transition planning.
Mechanism of Action
MECHANISM OF ACTION Follicular cysts are enlarged non-ovulatory follicles resulting from a malfunction of the neuroendocrine mechanism controlling follicular maturation and ovulation. Exogenous administration of agents possessing luteinizing hormone (LH) activity, such as pituitary extracts or…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
FACTREL careers are concentrated in veterinary/animal health commercial functions with zero linked open positions, reflecting a mature, stable product portfolio. Working on this product offers experience in niche veterinary markets but limited upside given LOE approaching status and minimal clinical pipeline activity.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.