EYDENZELT
LaunchBLAINJECTIONINJECTABLE
Approved
Oct 2025
Lifecycle
Launch
Competitive Pressure
30/100
Data completeness
4/8 — Partial
EYDENZELT by Celltrion is factor-a (vegf-a) and placental growth factor (plgf) are members of the vegf family of angiogenic factors that can act as mitogenic, chemotactic, and vascular permeability factors for endothelial cells. First approved in 2025.
Drug data last refreshed 2d ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
EYDENZELT is an aflibercept fusion protein (biosimilar or follow-on) administered by injection for vascular diseases driven by VEGF-A and PlGF signaling. It functions as a soluble decoy receptor that binds and sequesters VEGF-A and PlGF, preventing activation of VEGFR-1 and VEGFR-2 on endothelial cells and blocking neovascularization and vascular permeability. The drug targets angiogenic pathways implicated in retinal, choroidal, and potentially systemic vascular disorders.
Launch
Recent launch (Oct 2025) by Celltrion with moderate competitive pressure (30/100); early-stage teams focused on market penetration and clinical operations expansion.
Mechanism of Action
factor-A (VEGF-A) and placental growth factor (PlGF) are members of the VEGF family of angiogenic factors that can act as mitogenic, chemotactic, and vascular permeability factors for endothelial cells. VEGF acts via two receptor tyrosine kinases, VEGFR-1 and VEGFR-2, present on the surface of…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Why This Matters for Your Career
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.