EXTRANEAL

LOE Approaching

icodextrin, sodium chloride, sodium lactate, calcium chloride, magnesium chloride

NDAINTRAPERITONEALSOLUTION
Approved
Dec 2002
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4

Mechanism of Action

(icodextrin) as the primary osmotic agent. Icodextrin functions as a colloid osmotic agent to achieve ultrafiltration during long peritoneal dialysis dwells. Icodextrin acts in the peritoneal cavity by exerting osmotic pressure across small intercellular pores resulting in transcapillary…

Indications (1)

Clinical Trials (4)

NCT06492031N/ARecruiting

Observational Study of the Use of Extraneal in Peritoneal Dialysis in Patients

Started Jun 2024
889 enrolled
Chronic Renal Failure
NCT02166359N/ACompleted

Effect of Extraneal (Icodextrin) on Triglyceride Levels in PD Patients

Started Jun 2014
22 enrolled
End Stage Renal Disease
NCT01219959Phase 3Completed

Dianeal, Extraneal, Nutrineal (D-E-N) Versus Dianeal Only in Diabetic Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients

Started Oct 2010
71 enrolled
End Stage Renal Disease (ESRD)DiabetesCAPD
NCT00397358Phase 4Withdrawn

Effect of Extraneal (Icodextrin)on Triglyceride Levels in PD Patients

Started Nov 2006
0
Peritoneal DialysisHypertriglyceridemia