NDATOPICALAEROSOL, METERED
Approved
Dec 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
EXIDINE (chlorhexidine gluconate) by Becton Dickinson is clinical pharmacology periogard® (chlorhexidine gluconate oral rinse usp, 0. First approved in 1984.
Drug data last refreshed 8h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
EXIDINE (Chlorhexidine Gluconate) is a topical antimicrobial oral rinse that reduces bacterial plaque by 54-97% through broad-spectrum activity against aerobic and anaerobic organisms. It is indicated for oral hygiene and plaque reduction in dental and periodontal applications. The drug works by local antimicrobial action in the oral cavity, with approximately 30% retention in the mouth and slow release into oral fluids.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30%); brand teams should expect transition from growth to defensive positioning and smaller support footprints.
Mechanism of Action
CLINICAL PHARMACOLOGY PerioGard® (Chlorhexidine Gluconate Oral Rinse USP, 0.12%) provides antimicrobial activity during oral rinsing. The clinical significance of chlorhexidine gluconate oral rinse's antimicrobial activities is not clear. Microbiological sampling of plaque has shown a general…
Indications
Worked on EXIDINE at Becton Dickinson? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.