EVISTA
LOE ApproachingNDAORALTABLET
Approved
Sep 2007
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
5/8 — Partial
EVISTA by Eli Lilly and Company is agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (serm). Approved for invasive breast cancer, reduction of the risk of recurrence of breast cancer, reduction of risk of noninvasive breast cancer and 1 more indications. First approved in 2007.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
EVISTA (raloxifene) is an oral small-molecule selective estrogen receptor modulator (SERM) approved for reduction of invasive and noninvasive breast cancer risk in postmenopausal women. It acts as an estrogen agonist in bone, increasing bone mineral density and reducing fracture risk, while functioning as an antagonist in breast and uterine tissues. The drug binds to estrogen receptors and modulates tissue-specific estrogenic activity through differential recruitment of coactivators and corepressors.
$0.001BPart D
LOE ApproachingProduct is in late-stage lifecycle with minimal Part D spending ($1M, 2,802 claims in 2023), signaling a small, potentially stable team focused on market maintenance.
Mechanism of Action
agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM). The biological actions of raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (agonism) and blockade of estrogenic…
Indications (4)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.