NDAORALCAPSULEPriority Review
Approved
Jan 1989
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3
Mechanism of Action
CLINICAL PHARMACOLOGY General In animal studies, flutamide demonstrates potent antiandrogenic effects. It exerts its antiandrogenic action by inhibiting androgen uptake and/or by inhibiting nuclear binding of androgen in target tissues or both. Prostatic carcinoma is known to be androgen-sensitive…
Clinical Trials (3)
Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer
Started Nov 2016
206 enrolled
Prostate Cancer
Flutamide In the Prevention of Prostate Cancer in Patients With Neoplasia of the Prostate
Started Aug 2000
63 enrolled
Prostate Cancer
Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c
Started Dec 1996
341 enrolled
Prostatic Neoplasms