NDAORALCAPSULEPriority Review
Approved
Jan 1989
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
5
Data completeness
4/8 — Partial
Priority Review
EULEXIN (flutamide) by Merck & Co. is clinical pharmacology general in animal studies, flutamide demonstrates potent antiandrogenic effects. First approved in 1989.
Drug data last refreshed 11m ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Eulexin (flutamide) is an oral nonsteroidal antiandrogen that inhibits androgen uptake and nuclear binding in target tissues, used to treat androgen-sensitive prostatic carcinoma. It works by counteracting the effects of androgen in prostate cancer cells. The drug is rapidly absorbed and extensively metabolized, with its active alpha-hydroxylated metabolite reaching peak plasma concentrations within 2 hours.
$0.156MPart D
LOE ApproachingMinimal Part D activity and declining market presence indicate a mature product with shrinking commercial infrastructure and limited team expansion opportunities.
Mechanism of Action
CLINICAL PHARMACOLOGY General In animal studies, flutamide demonstrates potent antiandrogenic effects. It exerts its antiandrogenic action by inhibiting androgen uptake and/or by inhibiting nuclear binding of androgen in target tissues or both. Prostatic carcinoma is known to be androgen-sensitive…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.