ETHAMOLIN
LOE Approachingethanolamine oleate
NDAINJECTIONINJECTABLEPriority Review
Approved
Dec 1988
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
Priority Review
ETHAMOLIN (ethanolamine oleate) is clinical pharmacology when injected intravenously, ethamolin injection acts primarily by irritation of the intimal endothelium of the vein and produces a sterile dose-related inflammatory response. Approved for to prevent rebleeding, hypertension. First approved in 1988.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ETHAMOLIN (ethanolamine oleate) is an injectable sclerosing agent approved in 1988 for preventing rebleeding from esophageal varices. It works by inducing sterile inflammation and fibrosis of variceal veins through direct endothelial irritation and extravascular inflammatory response, leading to vein occlusion over 2.5 months. The oleic acid component drives inflammation while the ethanolamine component may inhibit clot formation.
LOE Approaching
Product is approaching loss of exclusivity with minimal linked job opportunities, suggesting a small, stable brand team focused on maintenance rather than growth.
Mechanism of Action
CLINICAL PHARMACOLOGY When injected intravenously, ETHAMOLIN Injection acts primarily by irritation of the intimal endothelium of the vein and produces a sterile dose-related inflammatory response. This results in fibrosis and possible occlusion of the vein. ETHAMOLIN Injection also rapidly…
Indications (2)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
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