NDATOPICALEMULSION
Approved
Oct 2003
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
relugolix, estradiol (E2), and norethindrone acetate (NETA). Relugolix is a non-peptide GnRH receptor antagonist that competitively binds to pituitary GnRH receptors, thereby reducing the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to decreased serum…
Indications (3)
heavy menstrual bleeding associated with uterine leiomyomas (fibroids) in premenopausal women [ see Clinical Studies () ]moderate to severe pain associated with endometriosis in premenopausal women [ see Clinical Studies () ]premenopausal women for the: management of heavy menstrual bleeding associated with uterine leiomyomas (fibroids)