ESBRIET

Peak

pirfenidone

NDAORALTABLET
Approved
Jan 2017
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

established.

Pharmacologic Class:

Pyridone

Clinical Trials (5)

NCT06241560Phase 2Recruiting

A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood

Started Mar 2026
20 enrolled
Idiopathic Pulmonary Fibrosis
NCT07015398Phase 1Completed

A Study of the Pharmacokinetic Interaction Between Pirfenidone, Nintedanib, and Nalbuphine Extended Release (NAL ER) in Healthy Participants

Started Jun 2025
NCT06070610Phase 1Completed

A Study in Healthy Men to Test Whether BI 1015550 Influences the Amount of Nintedanib and Pirfenidone in the Blood

Started Nov 2023
14 enrolled
Healthy
NCT04971746Phase 1Completed

Drug-drug Interaction Study with GLPG4716 and Nintedanib and Pirfenidone in Healthy Subjects

Started Jul 2021
58 enrolled
Healthy
NCT04258397Phase 2Unknown

Trial of Pirfenidone to Prevent Progression in Chronic Kidney Disease

Started Oct 2020
200 enrolled
Chronic Kidney Disease

Loss of Exclusivity

LOE Date
Mar 28, 2037
134 months away
Patent Expiry
Mar 28, 2037

Patent Records (5)

Patent #ExpiryTypeUse Code
8420674
Dec 18, 2027
U-2079
7767700
Dec 18, 2027
U-2080
8383150
May 10, 2028
Product
U-2361
7566729
Apr 22, 2029
U-2270
8592462
Apr 22, 2029
U-2060