NDAINJECTIONINJECTABLE
Approved
Jun 1964
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
ERYTHROCIN (erythromycin lactobionate) by Pfizer is clinical pharmacology erythromycin diffuses readily into most body fluids. Approved for penicillin-allergic patients, the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below, the severity of the infection requires immediate high serum levels of erythromycin. First approved in 1964.
Drug data last refreshed 3h ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ERYTHROCIN (erythromycin lactobionate) is an intravenous macrolide antibiotic that inhibits bacterial protein synthesis by binding to 50S ribosomal subunits. It is indicated for treatment of infections caused by susceptible organisms in penicillin-allergic patients and situations requiring immediate high serum antibiotic levels. The drug has broad gram-positive and gram-negative coverage including Legionella pneumophila, Mycoplasma pneumoniae, and Streptococcus species.
LOE Approaching
As a 60-year-old product nearing loss of exclusivity with moderate competitive pressure (30), brand teams face downsizing and consolidation rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Erythromycin diffuses readily into most body fluids. In the absence of meningeal inflammation, low concentrations are normally achieved in the spinal fluid but the passage of the drug across the blood-brain barrier increases in meningitis. Erythromycin crosses the placental…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.