NDAINJECTIONINJECTABLE
Approved
Jun 1964
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
ERYTHROCIN (erythromycin lactobionate) by Pfizer is clinical pharmacology erythromycin diffuses readily into most body fluids. Approved for penicillin-allergic patients, the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below, the severity of the infection requires immediate high serum levels of erythromycin. First approved in 1964.
Drug data last refreshed 7h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Erythromycin lactobionate is an injectable macrolide antibiotic administered intravenously for infections requiring immediate high serum levels. It works by inhibiting bacterial protein synthesis through binding to 50S ribosomal subunits. Indicated for penicillin-allergic patients and infections caused by susceptible gram-positive and gram-negative organisms including Staphylococcus aureus, Streptococcus species, Legionella pneumophila, and Mycoplasma pneumoniae.
LOE Approaching
Legacy injectable product in LOE approaching phase with moderate competitive pressure (30), indicating stable but declining brand portfolio engagement.
Mechanism of Action
CLINICAL PHARMACOLOGY Erythromycin diffuses readily into most body fluids. In the absence of meningeal inflammation, low concentrations are normally achieved in the spinal fluid but the passage of the drug across the blood-brain barrier increases in meningitis. Erythromycin crosses the placental…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.