NDAINTRAVENOUSSOLUTION
Approved
Oct 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
5/8 — Partial
EPHEDRINE SULFATE (ephedrine sulfate) by Pfizer is α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. First approved in 2020.
Drug data last refreshed 2h ago · AI intelligence enriched 4w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Ephedrine sulfate is an IV sympathomimetic agent approved by the FDA in October 2020 that activates α- and β-adrenergic receptors while indirectly releasing norepinephrine from sympathetic neurons. It is indicated for acute hypotension management in clinical settings, working through direct adrenergic stimulation and indirect sympathetic nerve activation to increase arterial pressure, cardiac output, and peripheral resistance.
Peak13.2 years to LOE
Product is at peak lifecycle stage with no competitive pressure, indicating stable team structure but limited growth opportunities in commercial expansion.
Mechanism of Action
α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. Pressor effects by direct alpha- and beta-adrenergic receptor activation are mediated by increases in arterial pressures, cardiac output, and peripheral resistance. Indirect adrenergic…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions
Started Apr 2006
34 enrolled
Healthy
Career Relevance
Working on ephedrine sulfate offers stable, mature-stage portfolio experience in acute care with minimal competitive pressure but also limited growth opportunities. The safety profile and post-market monitoring demands create strong roles in pharmacovigilance and medical affairs focused on risk management.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.