NDAINTRAVENOUSSOLUTION
Approved
Oct 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
5/8 — Partial
EPHEDRINE SULFATE (ephedrine sulfate) by Pfizer is α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. First approved in 2020.
Drug data last refreshed 3h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Ephedrine sulfate is a sympathomimetic amine administered intravenously that activates α- and β-adrenergic receptors while indirectly releasing norepinephrine from sympathetic neurons. It is used to restore and maintain blood pressure in acute hypotensive episodes during anesthesia. The pressor effects are mediated through increases in arterial pressure, cardiac output, and peripheral resistance.
Peak13.6 years to LOE
Peak-stage intravenous product with Pfizer backing in established surgical/anesthesia market; stable team structure focused on hospital and perioperative channels.
Mechanism of Action
α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. Pressor effects by direct alpha- and beta-adrenergic receptor activation are mediated by increases in arterial pressures, cardiac output, and peripheral resistance. Indirect adrenergic…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions
Started Apr 2006
34 enrolled
Healthy
Career Relevance
Working on ephedrine sulfate offers stability in a peak-stage, low-competition specialty product with secure patent protection through 2040 and established clinical utility in anesthesia. Roles focus on hospital relationships, clinician engagement, and perioperative market penetration rather than primary care or consumer-facing functions.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.