NDAORALFOR SOLUTION
Approved
Aug 2013
Lifecycle
Peak
Competitive Pressure
0/100
Data completeness
4/8 — Partial
EPANED KIT (enalapril maleate) by R-Pharm US is mechanism of action enalapril, after hydrolysis to enalaprilat, inhibits angiotensin-converting enzyme (ace) in human subjects and animals. Approved for hypertension. First approved in 2013.
Drug data last refreshed Yesterday · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
EPANED KIT is an oral solution formulation of enalapril maleate, an ACE inhibitor that treats hypertension by blocking angiotensin-converting enzyme and suppressing the renin-angiotensin-aldosterone system. After hydrolysis to enalaprilat, the drug inhibits conversion of angiotensin I to angiotensin II, reducing vasopressor activity and aldosterone secretion. The kit formulation enables flexible dosing for patients requiring customized hypertension management.
Peak6.5 years to LOE
Product is at peak commercial maturity with stable market position; team size likely focused on maintenance and managed care strategies rather than growth-stage expansion.
Mechanism of Action
Mechanism of Action Enalapril, after hydrolysis to enalaprilat, inhibits angiotensin-converting enzyme (ACE) in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates…
Indications (1)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.