ELUXADOLINE

Pre-Launch

eluxadoline

ANDAORALTABLET
Lifecycle
Pre-Launch
Clinical Trials
2

Mechanism of Action

mu-opioid receptor agonist; eluxadoline is also a delta opioid receptor antagonist and a kappa opioid receptor agonist. The binding affinities (Ki) of eluxadoline for the human mu and delta opioid receptors are 1.8 nM and 430 nM, respectively. The binding affinity (Ki) of eluxadoline for the human…

Clinical Trials (2)

NCT04880876Phase 3Enrolling By Invitation

A Study Evaluating Oral Eluxadoline Administered to Pediatric Participants With Irritable Bowel Syndrome With Diarrhea (IBS-D)

Started Aug 2021
124 enrolled
Irritable Bowel Syndrome
NCT03339128Phase 2Recruiting

Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

Started Nov 2017
95 enrolled
Irritable Bowel Syndrome