NDATOPICALCREAM
Approved
Aug 1989
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
5
Data completeness
4/8 — Partial
ELIMITE (permethrin) by Aurobindo Pharma is clinical pharmacology permethrin, a pyrethroid, is active against a broad range of pests including lice, ticks, fleas, mites, and other arthropods. First approved in 1989.
Drug data last refreshed 1h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ELIMITE (permethrin 5% cream) is a topical pyrethroid insecticide that disrupts sodium channel function in arthropod nerve membranes, causing paralysis and death of lice, mites, ticks, and fleas. It is rapidly metabolized to inactive metabolites and minimally absorbed systemically (≤2% of applied dose). The drug is indicated for parasitic infestations treatable via topical application.
LOE Approaching
Product is in late-stage lifecycle with modest competitive pressure (30/100), signaling a consolidated, cost-focused team focused on retention rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Permethrin, a pyrethroid, is active against a broad range of pests including lice, ticks, fleas, mites, and other arthropods. It acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated. Delayed repolarization…
Pharmacologic Class:
Pyrethroid
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (5)
Comparison of Oral Ivermectin and Permethrin 5% Lotion in Treatment of Pediculosis Capitis
Started Mar 2022
60 enrolled
Pediculosis
Comparison of Topical 5% Permethrin and Topical 10% Sulfur in the Treatment of Scabies
Started Mar 2022
60 enrolled
Scabies
Comparative Study Between Topical Permethrin 5% and Oral Ivermectin for the Treatment of Scabies
Started Jun 2021
100 enrolled
Scabies
A Study to Evaluate the Therapeutic Equivalence of Generic Permethrin Cream 5% to Elimite® in the Treatment of Scabies
Started Sep 2015
250 enrolled
Scabies
A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies
Started Apr 2014
130 enrolled
Scabies
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.