ELDEPRYL

LOE Approaching

selegiline hydrochloride

NDAORALCAPSULE
Approved
May 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

CLINICAL PHARMACOLOGY The mechanisms accounting for selegiline's beneficial adjunctive action in the treatment of Parkinson's disease are not fully understood. Inhibition of monoamine oxidase, type B, activity is generally considered to be of primary importance; in addition, there is evidence that…