DULOXETINE HYDROCHLORIDE (duloxetine) by Hetero is 12. Approved for the following conditions: major depressive disorder (mdd) in adults generalized anxiety disorder (gad) in adults, older diabetic peripheral neuropathic pain (dpnp) in adults fibromyalgia (fm) in adults chronic musculoskeletal pain in adults, anxiety. First approved in 2019.
Drug data last refreshed 20h ago
12.1 Mechanism of Action Although the exact mechanisms of the antidepressant, central pain inhibitory and anxiolytic actions of duloxetine in humans are unknown, these actions are believed to be related to its potentiation of serotonergic and noradrenergic activity in the CNS. 12.2 Pharmacodynamics…
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