NDAORALCAPSULE
Approved
Jan 1941
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
5/8 — Partial
DRISDOL (ergocalciferol) by Molecular Devices is clinical pharmacology the in vivo synthesis of the major biologically active metabolites of vitamin d occurs in two steps. First approved in 1941.
Drug data last refreshed 5h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DRISDOL (ergocalciferol) is a vitamin D2 provitamin compound administered orally in capsule form that promotes active absorption of calcium and phosphorus in the small intestine to support bone mineralization. The drug works through hepatic and renal hydroxylation to generate active metabolites that regulate serum calcium and phosphate levels. It has been approved since 1941 and remains a foundational micronutrient therapy for vitamin D deficiency.
LOE Approaching
LOE approaching creates a challenging environment; the product is transitioning toward commoditization with limited team expansion likely.
Mechanism of Action
CLINICAL PHARMACOLOGY The in vivo synthesis of the major biologically active metabolites of vitamin D occurs in two steps. The first hydroxylation of ergocalciferol takes place in the liver (to 25-hydroxyvitamin D) and the second in the kidneys (to 1, 25-dihydroxyvitamin D). Vitamin D metabolites…
Pharmacologic Class:
Provitamin D2 Compound
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patients
Started Jul 2010
50 enrolled
Pruritis
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.