NDAORALCAPSULE
Approved
Jan 1941
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
DRISDOL (ergocalciferol) by Molecular Devices is clinical pharmacology the in vivo synthesis of the major biologically active metabolites of vitamin d occurs in two steps. First approved in 1941.
Drug data last refreshed 12h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DRISDOL (ergocalciferol) is a vitamin D2 provitamin compound administered orally as a capsule that promotes active calcium and phosphorus absorption in the small intestine and regulates bone mineralization. The drug undergoes hepatic and renal hydroxylation to generate active metabolites (25-hydroxyvitamin D and 1,25-dihydroxyvitamin D) with a 10–24 hour lag to therapeutic effect. It is used to treat vitamin D deficiency and related metabolic bone disorders.
LOE Approaching
Product is in late-stage lifecycle with moderate competitive pressure (30/100), signaling a mature commercial team focused on maintenance and cost management rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY The in vivo synthesis of the major biologically active metabolites of vitamin D occurs in two steps. The first hydroxylation of ergocalciferol takes place in the liver (to 25-hydroxyvitamin D) and the second in the kidneys (to 1, 25-dihydroxyvitamin D). Vitamin D metabolites…
Pharmacologic Class:
Provitamin D2 Compound
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patients
Started Jul 2010
50 enrolled
Pruritis
Worked on DRISDOL at Molecular Devices? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.