DORYX
LOE Approachingdoxycycline hyclate
NDAORALCAPSULE, DELAYED RELEASE
Approved
Jul 1985
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
tetracycline-class antimicrobial drug [ see ].
Indications (21)
Rocky Mountain spotted fevertyphus feverthe typhus groupQ feverrickettsialpoxtick fevers caused by Rickettsiaethe following sexually transmitted infections: Uncomplicated urethralendocervicalrectal infections in adults caused by Chlamydia trachomatisthe following respiratory tract infections: Respiratory tract infections caused by Mycoplasma pneumoniaeinfections caused by the following microorganismsbacteriological testing indicates appropriate susceptibility to the drug: Respiratory tract infections caused by Haemophilus influenzaethe following specific bacterial infections: Relapsing fever due to Borrelia recurrentisinfections caused by the following gram-negative microorganismsthe following ophthalmic infections: Trachoma caused by Chlamydia trachomatisalthough the infectious agent is not always eliminatedAnthrax due to Bacillus anthracisincluding inhalational anthrax (post-exposure): to reduce the incidenceprogression of disease following exposure to aerosolized Bacillus anthracismalaria due to Plasmodium falciparum in short-term travelers (less than 4 months) to areas with chloroquine and/or pyrimethamine-sulfadoxine resistant strains [ seeincidence