NDAINJECTIONINJECTABLE
Approved
Jul 1981
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
DOPAMINE HYDROCHLORIDE (dopamine hydrochloride) by Baxter is clinical pharmacology dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (dopa). Approved for hemodynamic status in patients in shock. First approved in 1981.
Drug data last refreshed 3d ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Dopamine hydrochloride is a natural catecholamine injectable used to manage hemodynamic instability in patients experiencing shock. It works through dose-dependent activation of dopamine, beta-1, and alpha-1 adrenergic receptors, producing rapid inotropic and chronotropic cardiac effects within minutes of IV administration. The drug has a short plasma half-life of approximately 2 minutes, allowing for rapid titration and offset in acute care settings.
LOE Approaching
This is a mature, off-patent critical care product approaching end-of-life with limited commercial growth opportunities and likely small or consolidating brand teams focused on supply chain and hospital relationships.
Mechanism of Action
CLINICAL PHARMACOLOGY Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal…
Worked on DOPAMINE HYDROCHLORIDE at Baxter? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.