DOCETAXEL
PeakNDAINJECTIONINJECTABLE
Approved
Mar 2014
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
DOCETAXEL by Pfizer is 12. Approved for metastatic breast cancer after failure of prior chemotherapy, metastatic non-small cell lung cancer after failure of prior platinum-based chemotherapy, locally advanced and 2 more indications. First approved in 2014.
Drug data last refreshed 11h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Docetaxel is a small-molecule taxane chemotherapy agent that stabilizes microtubules by promoting tubulin assembly and inhibiting disassembly, thereby disrupting mitosis and inducing cell death. It is approved for metastatic breast cancer, non-small cell lung cancer (NSCLC), and gastric cancer after failure of prior chemotherapy. Docetaxel represents a foundational cytotoxic backbone in solid tumor oncology.
Peak
Docetaxel is at peak maturity with moderate competitive pressure (30/100), suggesting stable but not expanding commercial teams; most hiring activity is likely in field maintenance and cost-containment roles.
Mechanism of Action
12.1 Mechanism of Action Docetaxel is an antineoplastic agent that acts by disrupting the microtubular network in cells that is essential for mitotic and interphase cellular functions. Docetaxel binds to free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.