DOBUTREX
LOE ApproachingNDAINJECTIONINJECTABLEPriority Review
Approved
Jul 1978
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 39m ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DOBUTREX (dobutamine) is a small-molecule inotropic agent administered by intravenous injection to increase cardiac contractility and improve hemodynamic function in acute decompensated heart failure and cardiogenic shock. It works as a beta-1 adrenergic agonist, directly stimulating myocardial contractility and peripheral vasodilation. The drug is indicated for patients requiring short-term inotropic support in hospital settings.
LOE Approaching
As an established injectable in LOE-approaching phase with low competitive pressure (30%), the product likely operates with a stable, lean commercial team focused on defensive positioning rather than expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Efficacy and Safety of Treatment With Simdax® Versus Dobutrex® in Decompensated Heart Failure Patients.
Started Nov 2002
60 enrolled
Heart Failure
Career Relevance
Working on DOBUTREX offers limited career growth given the product's LOE-approaching stage and zero linked job openings; roles are primarily focused on maintaining market position and managing decline. Career advancement on this asset is constrained, making it a stabilization role rather than a growth opportunity.
Product Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.