DOBUTREX
LOE ApproachingNDAINJECTIONINJECTABLEPriority Review
Approved
Jul 1978
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 21h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DOBUTREX (dobutamine) is an injectable small-molecule inotropic agent approved in 1978 for acute heart failure and cardiogenic shock. It works as a beta-1 adrenergic agonist to increase cardiac contractility and improve blood flow. The drug is administered intravenously in acute care hospital settings.
LOE Approaching
As a legacy injectable approaching loss of exclusivity, DOBUTREX team sizes are likely stable or contracting with focus on operational efficiency and transition planning.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Efficacy and Safety of Treatment With Simdax® Versus Dobutrex® in Decompensated Heart Failure Patients.
Started Nov 2002
60 enrolled
Heart Failure
Career Relevance
DOBUTREX roles are primarily operational and commercial-execution focused, with limited visibility in job postings. This product is best suited for early-career professionals seeking stable specialty pharma or hospital sales experience, or mid-career professionals transitioning into operational/supply-chain functions.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.