DOBUTREX
LOE ApproachingNDAINJECTIONINJECTABLEPriority Review
Approved
Jul 1978
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 6d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DOBUTREX (dobutamine) is a small-molecule inotropic agent administered by injection, primarily indicated for acute decompensated heart failure and cardiogenic shock. It works as a beta-1 adrenergic agonist to increase cardiac contractility and improve hemodynamics in hospitalized patients requiring short-term inotropic support.
LOE Approaching
Late-stage product with moderate competitive pressure (30%) signals a consolidating team; career growth opportunities are limited as the brand prepares for generic erosion or lifecycle transition.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Efficacy and Safety of Treatment With Simdax® Versus Dobutrex® in Decompensated Heart Failure Patients.
Started Nov 2002
60 enrolled
Heart Failure
Career Relevance
Working on DOBUTREX offers limited career growth due to zero linked job openings and LOE-approaching lifecycle status. Roles are primarily defensive, focused on managed care negotiations, institutional relationships, and regulatory compliance rather than expansion or innovation.
Brand Manager
Worked on DOBUTREX at Eli Lilly and Company? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.