Data completeness
2/8 — Basic
DIZAC (diazepam) by Pfizer is mechanism of action although the precise mechanism by which diazepam exerts its antiseizure effects is unknown, animal and in vitro studies suggest that diazepam acts to suppress seizures through an interaction with γ-aminobutyric acid (gaba) receptors of the a-type (gaba a ).
Drug data last refreshed 4h ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DIZAC (diazepam) is an injectable benzodiazepine that acts as a GABA-A receptor agonist to suppress seizure activity and neuronal hyperexcitability. It enhances the binding of GABA, the major inhibitory neurotransmitter in the CNS, allowing chloride influx that reduces neuronal depolarization. DIZAC is indicated for acute seizure management and anxiety disorders requiring rapid onset parenteral therapy.
Pre-Launch
As a pre-launch product, DIZAC teams are focused on buildout, regulatory finalization, and pre-commercial preparation with modest current headcount.
Mechanism of Action
Mechanism of Action Although the precise mechanism by which diazepam exerts its antiseizure effects is unknown, animal and in vitro studies suggest that diazepam acts to suppress seizures through an interaction with γ-aminobutyric acid (GABA) receptors of the A-type (GABA A ). GABA, the major…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (7)
A Study to Assess the Time to Onset of Action of Staccato Alprazolam Versus Midazolam and Diazepam in Healthy Participants
Started Jun 2025
55 enrolled
Healthy Participants
Safety and Tolerability Study of Diazepam Buccal Film (DBF) in Subjects With Epilepsy
Started Jan 2018
149 enrolled
Epilepsy
Treatment Of Alcohol Withdrawal Syndrome: Dexmedetomidine Vs Diazepam In A Hospital O'horán
Started Nov 2017
2 enrolled
Alcohol Withdrawal Delirium
Pharmacokinetics and Safety Study of Diazepam Buccal Film (DBF) in Pediatric Subjects With Epilepsy
Started Aug 2017
24 enrolled
Epilepsy
A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers
Started Feb 2011
24 enrolled
Epilepsy
Worked on DIZAC at Pfizer? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.