DIPYRIDAMOLE

Post-LOE

dipyridamole

ANDAORALTABLET
Approved
Apr 2006
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
12

Mechanism of Action

Mechanism of Action Dipyridamole inhibits the uptake of adenosine into platelets, endothelial cells and erythrocytes in vitro and in vivo ; the inhibition occurs in a dose-dependent manner at therapeutic concentrations (0.5-1.9 mg/mL). This inhibition results in an increase in local concentrations…

Pharmacologic Class:

Platelet Aggregation Inhibitor

Clinical Trials (5)

NCT00808314Phase 4Unknown

Lexiscan(TM) Rb-82 Myocardial Perfusion PET: A Comparison With Dipyridamole Stress

Started Dec 2008
32 enrolled
Coronary Artery Disease
NCT02262793Phase 1Completed

Relative Bioavailability of Telmisartan and Dipyridamole After Co-administration Compared to the Bioavailability of Telmisartan or Dipyridamole Alone in Healthy Female and Male Subjects

Started May 2004
24 enrolled
Healthy
NCT00129038Phase 4Completed

Modified-release Dipyridamole/Aspirin (200mg/25mg bd) Versus Aspirin (75mg) in Aspirin-resistant Patients

Started Apr 2004
11 enrolled
Coronary Arteriosclerosis
NCT02273557Phase 1Completed

Bioavailability of Dipyridamole of Asasantin p.o. in Three Experimental Formulations Relative to the Standard Formulation in Healthy Male Subjects

Started Jan 2003
19 enrolled
Healthy
NCT00906035N/ATerminated

The Vascular Biology of Dipyridamole in Peripheral Arterial Disease (PAD)

Started Sep 2002
25 enrolled
Peripheral Arterial Disease