NDATOPICALOINTMENT
Approved
Apr 1976
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
19
Data completeness
3/8 — Basic
DIPROSONE (betamethasone dipropionate) by Merck & Co. is [see ] . First approved in 1976.
Drug data last refreshed Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DIPROSONE (betamethasone dipropionate) is a topical corticosteroid ointment approved in 1976 for treating inflammatory skin and connective tissue diseases including psoriasis, atopic dermatitis, and chronic rhinosinusitis. It works by modulating cellular signaling, immune function, and inflammation through corticosteroid mechanisms, though the precise mechanism for certain fungal indications remains unclear. This is a mature, established therapy in the dermatology and allergy space.
LOE Approaching
As a mature product approaching loss of exclusivity, the brand team is likely focused on lifecycle management, generic defense strategies, and cost containment rather than expansion; expect smaller dedicated teams and emphasis on operational efficiency.
Mechanism of Action
[see ] . Betamethasone dipropionate is a corticosteroid. Corticosteroids play a role in cellular signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action for the treatment of tinea pedis, tinea cruris and tinea corporis is unknown.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (19)
The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS)
Started Aug 2023
24 enrolled
Chronic Rhinosinusitis (Diagnosis)
A Study to Assess Treatment Satisfaction, Patient-reported Outcomes, Effectiveness, and Safety of a Fixed-dose Combination of Calcipotriene/Betamethasone Dipropionate PAD Cream in the Treatment of Mild-to-moderate Plaque Psoriasis of the Scalp in Adults
Started Jun 2023
291 enrolled
Plaque Psoriasis
Treatment of Eosinophilic Chronic Rhinosinusitis Utilizing Betamethasone Dipropionate Nasal Cream
Started Feb 2022
2 enrolled
Chronic Rhinosinusitis (Diagnosis)
Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamics Effect of Calcipotriol/Betamethasone Dipropionate in a New Administration Form in Subjects With Chronic Plaque Psoriasis.
Started Apr 2019
15 enrolled
Psoriasis Vulgaris
Skin Irritation of LEO 90100 Foam (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Healthy Japanese Subjects
Started Jan 2018
20 enrolled
Psoriasis Vulgaris
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.