DIFLUCAN IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

LOE Approaching

fluconazole

NDAINJECTIONINJECTABLE
Approved
Jan 1990
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

CLINICAL PHARMACOLOGY Pharmacokinetics and Metabolism The pharmacokinetic properties (PK) of fluconazole are similar following administration by the intravenous or oral routes. In normal volunteers, the bioavailability of orally administered fluconazole is over 90% compared with intravenous…

Clinical Trials (5)

NCT00002010N/ACompleted

Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis

MeningitisHIV Infections
NCT00002306N/ACompleted

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B

Meningitis, CryptococcalHIV Infections
NCT00002341N/ACompleted

A Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With Fluconazole

Candidiasis, OralHIV Infections
NCT00002077N/ACompleted

An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

Meningitis, CryptococcalHIV Infections
NCT00002305N/ACompleted

A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis

Meningitis, CryptococcalHIV Infections