DIFLUCAN IN SODIUM CHLORIDE 0.9%

LOE ApproachingSM

fluconazole

NDAINJECTIONINJECTABLE
Approved
Jan 1990
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

CLINICAL PHARMACOLOGY Pharmacokinetics and Metabolism The pharmacokinetic properties (PK) of fluconazole are similar following administration by the intravenous or oral routes. In normal volunteers, the bioavailability of orally administered fluconazole is over 90% compared with intravenous…

Clinical Trials (5)

NCT00002325N/ACompleted

A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common

MycosesHIV InfectionsCoccidioidomycosis
NCT00002339Phase 3Completed

A Study of Fluconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems

100 enrolled
Candidiasis, EsophagealHIV Infections
NCT00002282N/ACompleted

A Comparison of the Safety and Effectiveness of Fluconazole or Clotrimazole in the Treatment of Fungal Infections of the Mouth and Throat in Patients With AIDS

Candidiasis, OralHIV Infections
NCT00002040N/ACompleted

Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

Meningitis, CryptococcalHIV Infections
NCT00002068N/ACompleted

A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

Meningitis, CryptococcalHIV Infections