DIAZEPAM

LOE Approaching

diazepam

NDAINJECTIONINJECTABLE
Approved
Dec 1990
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3

Mechanism of Action

CLINICAL PHARMACOLOGY In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side…

Pharmacologic Class:

Benzodiazepine

Clinical Trials (3)

NCT07020988Phase 1Completed

A Study to Assess the Time to Onset of Action of Staccato Alprazolam Versus Midazolam and Diazepam in Healthy Participants

Started Jun 2025
55 enrolled
Healthy Participants
NCT01364558Phase 1Completed

A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers

Started Feb 2011
24 enrolled
Epilepsy
NCT00319501Phase 3Completed

Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures.

Started Jan 2006
234 enrolled
SeizuresEpilepsies, PartialEpilepsy, Complex Partial+2 more