NDAORALCAPSULE, EXTENDED RELEASE
Approved
Jan 1962
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
3/8 — Basic
DIAMOX (acetazolamide) by Teva is clinical pharmacology acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion (eg, some types of glaucoma), in the treatment of certain convulsive disorders (eg, epilepsy) and in the promotion of diuresis in instances of abnormal fluid retention (eg, cardiac edema). First approved in 1962.
Drug data last refreshed 16h ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Acetazolamide is a potent carbonic anhydrase inhibitor marketed as DIAMOX, used to treat glaucoma, epilepsy, diuretic-responsive edema, and acute mountain sickness. It works by inhibiting the enzyme carbonic anhydrase, which decreases aqueous humor secretion in the eye, reduces abnormal neuronal discharge in the CNS, and promotes renal sodium and water excretion. The drug is administered orally as an extended-release capsule.
LOE Approaching
As a legacy product approaching loss of exclusivity with moderate competitive pressure (30%), brand teams face declining revenue trajectories and likely resource consolidation.
Mechanism of Action
CLINICAL PHARMACOLOGY Acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion (eg, some types of glaucoma), in the treatment of certain convulsive disorders (eg, epilepsy) and in the promotion of diuresis in instances of abnormal fluid retention (eg,…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.