NDAORALTABLETPriority Review
Approved
Jul 1953
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
4/8 — Partial
Priority Review
DIAMOX (acetazolamide) by Teva is clinical pharmacology acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion (eg, some types of glaucoma), in the treatment of certain convulsive disorders (eg, epilepsy) and in the promotion of diuresis in instances of abnormal fluid retention (eg, cardiac edema). Approved for acute mountain sickness, high altitude cerebral edema. First approved in 1953.
Drug data last refreshed Yesterday · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DIAMOX (acetazolamide) is a potent carbonic anhydrase inhibitor oral tablet approved in 1953 for acute mountain sickness and high altitude cerebral edema. It works by inhibiting the enzyme carbonic anhydrase, reducing aqueous humor secretion in the eye and promoting diuresis in the kidney, while also stabilizing central nervous system function. The drug is indicated for altitude-related conditions where it reduces symptoms such as headache, nausea, shortness of breath, dizziness, and sleep disturbance in climbers undergoing rapid ascent.
LOE Approaching
As a product approaching loss of exclusivity with moderate competitive pressure (30%), the brand team faces near-term revenue headwinds, likely resulting in smaller commercial operations focused on niche positioning.
Mechanism of Action
CLINICAL PHARMACOLOGY Acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion (eg, some types of glaucoma), in the treatment of certain convulsive disorders (eg, epilepsy) and in the promotion of diuresis in instances of abnormal fluid retention (eg,…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.