DIACOMIT

Peak

stiripentol

NDAORALFOR SUSPENSIONPriority Review
Approved
Aug 2018
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
2

Mechanism of Action

unknown. Possible mechanisms of action include direct effects mediated through the gamma-aminobutyric acid (GABA) A receptor and indirect effects involving inhibition of cytochrome P450 activity with resulting increase in blood levels of clobazam and its active metabolite.

Clinical Trials (2)

NCT02607904Phase 2Completed

An Open-label Extension Trial to Investigate Possible Drug-drug Interactions Between Stiripentol or Valproate and Cannabidiol in Patients With Epilepsy

Started Dec 2016
30 enrolled
Epilepsy
NCT02607891Phase 2Completed

A Study of Possible Drug-drug Interactions Between Stiripentol or Valproate and Cannabidiol in Patients With Epilepsy

Started Nov 2016
35 enrolled
Epilepsy