NDAINJECTIONINJECTABLEPriority Review
Approved
Apr 1968
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
Priority Review
DESFERAL (deferoxamine mesylate) by Gland Pharma is reactions. First approved in 1968.
Drug data last refreshed 14h ago · AI intelligence enriched 5d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DESFERAL (deferoxamine mesylate) is an injectable iron chelator that binds and removes excess iron from the body, particularly from ferritin and hemosiderin stores. It is used to treat chronic iron overload from repeated blood transfusions or hemochromatosis. The drug works by forming stable complexes with ferric iron, facilitating its excretion without affecting iron in functional proteins like hemoglobin or cytochromes.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100), signaling potential team consolidation and shift toward generic transition management.
Mechanism of Action
reactions. It readily chelates iron from ferritin and hemosiderin but not readily from transferrin; it does not combine with the iron from cytochromes and hemoglobin. Deferoxamine mesylate does not cause any demonstrable increase in the excretion of electrolytes or trace metals. Theoretically, 100…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on DESFERAL offers stability in a niche therapeutic area but limited growth trajectory due to LOE approaching and declining competitive position. Career advancement opportunities are concentrated in managing the transition to generic competition and maintaining market access rather than driving expansion or innovation.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.