DEPAKOTE ER
LOE ApproachingNDAOralTablet, Extended Release
Approved
Dec 2002
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
13
Data completeness
5/8 — Partial
DEPAKOTE ER by Abbott is tract. Approved for acute manic, mixed episodes associated with bipolar disorder, with and 4 more indications. First approved in 2002.
Drug data last refreshed 8h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DEPAKOTE ER is an extended-release oral tablet containing valproate, approved in 2002 for acute manic and mixed episodes associated with bipolar disorder (with or without psychotic features) and migraine headache prevention. The mechanism is not fully established, but is thought to involve increased brain concentrations of gamma-aminobutyric acid (GABA).
$11MPart D
LOE ApproachingProduct is approaching loss of exclusivity with modest Part D spending ($11M) and 17,549 claims in 2023, indicating a mature market with stable but limited team expansion.
Mechanism of Action
tract. The mechanisms by which valproate exerts its therapeutic effects have not been established. It has been suggested that its activity in epilepsy is related to increased brain concentrations of gamma-aminobutyric acid (GABA).
Indications (7)
Worked on DEPAKOTE ER at Abbott? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.