DEMECLOCYCLINE HYDROCHLORIDE (demeclocycline hydrochloride) by Pfizer is clinical pharmacology pharmacokinetics the absorption of demeclocycline is slower than that of tetracycline. Approved for infections caused by the following gram-negative microorganisms, bacteriologic testing indicates appropriate susceptibility to the drug: escherichia coli, infections caused by the following gram-positive microorganisms and 7 more indications. First approved in 2004.
Drug data last refreshed 18h ago
CLINICAL PHARMACOLOGY Pharmacokinetics The absorption of demeclocycline is slower than that of tetracycline. The time to reach the peak concentration is about 4 hours. After a 150 mg oral dose of demeclocycline tablet, the mean concentrations at 1 hour and 3 hours are 0.46 and 1.22 mcg/mL (n = 6),…
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