DELSYM
LOE Approachingdextromethorphan
NDAORALSUSPENSION, EXTENDED RELEASE
Approved
Oct 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
DELSYM (dextromethorphan) is uncompetitive nmda receptor antagonists [moa]. First approved in 1982.
Drug data last refreshed 4d ago
Mechanism of Action
Uncompetitive NMDA Receptor Antagonists
Pharmacologic Class:
Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants
Started Mar 2026
42 enrolled
Healthy Participants
Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder
Started Nov 2025
30 enrolled
Major Depressive Disorder (MDD)
Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder
Started May 2025
80 enrolled
Major Depressive Disorder (MDD)
Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir
Started Mar 2022
48 enrolled
Malaria
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Started Oct 2017
601 enrolled
Agitation in Patients With Dementia of the Alzheimer's Type
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.