DEFERASIROX (deferasirox) by Fosun Pharma is (deferasirox) is an orally active chelator that is selective for iron (as fe). Approved for chronic iron overload in patients 10 years of age, older with non-transfusion-dependent thalassemia (ntdt) syndromes, a liver iron (fe) concentration (lic) of at least 5 mg fe per gram of dry weight and 4 more indications. First approved in 2020.
Drug data last refreshed 20h ago
(deferasirox) is an orally active chelator that is selective for iron (as Fe). It is a tridentate ligand that binds iron with high affinity in a 2:1 ratio. Although deferasirox has very low affinity for zinc and copper there are variable decreases in the serum concentration of these trace metals…
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Early and Low Dose Deferasirox (3.5 mg/kg FCT) to Suppress NTBI and LPI as Early Intervention to Prevent Tissue Iron Overload in Lower Risk MDS
Evaluating Low-dose Deferasirox (DFX) in Patients With Low-risk MDS Resistant or Relapsing After ESA Agents
Safety Study of Crushed Deferasirox Film Coated Tablets in Pediatric Patients With Transfusional Hemosiderosis
Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)
Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet