NDAOPHTHALMIC, OTICSOLUTION/DROPS
Approved
Sep 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Data completeness
4/8 — Partial
DECADRON (dexamethasone sodium phosphate) by Merck & Co. is clinical pharmacology naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Approved for ataxia telangiectasia, atopic keratoconjunctivitis, peripheral arterial disease and 3 more indications. First approved in 1959.
Drug data last refreshed 23h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DECADRON (dexamethasone sodium phosphate) is a synthetic glucocorticoid indicated for potent anti-inflammatory and immunomodulatory effects across multiple organ systems. Formulated as ophthalmic and otic drops, it treats conditions ranging from ataxia telangiectasia to atopic keratoconjunctivitis and perioperative inflammation. Unlike natural glucocorticoids, dexamethasone lacks significant sodium-retaining properties while maintaining powerful anti-inflammatory activity.
LOE Approaching
With lifecycle in LOE approaching status and no current Part D spending data reported, the brand team is likely in optimization mode preparing for generic erosion and transition strategies.
Mechanism of Action
CLINICAL PHARMACOLOGY Naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, including dexamethasone, are primarily used for their potent…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.