NDAORALTABLET
Approved
Sep 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
5/8 — Partial
DDAVP (desmopressin acetate) by Ferring Pharmaceuticals is clinical pharmacology ddavp tablets contain as active substance, desmopressin acetate, a synthetic analogue of the natural hormone arginine vasopressin. Approved for primary nocturnal enuresis. First approved in 1995.
Drug data last refreshed Yesterday · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DDAVP (desmopressin acetate) is a synthetic analogue of arginine vasopressin that acts as an antidiuretic agent. It is primarily indicated for primary nocturnal enuresis and central diabetes insipidus, working by increasing urine osmolality and reducing urinary output. The oral tablet formulation has approximately 5% bioavailability compared to intranasal administration, with onset of antidiuretic effect occurring around 1 hour and maximum effect at 4-7 hours.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30), signaling a contracting team focused on brand defense and market maintenance rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY DDAVP Tablets contain as active substance, desmopressin acetate, a synthetic analogue of the natural hormone arginine vasopressin. Central Diabetes Insipidus Dose response studies in patients with diabetes insipidus have demonstrated that oral doses of 0.025 mg to 0.4 mg…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.