NDAORALCAPSULEPriority Review
Approved
Nov 1957
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Priority Review
Drug data last refreshed 13h ago · AI intelligence enriched 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DARVON COMPOUND is a fixed-dose combination oral capsule containing propoxyphene hydrochloride (a weak opioid), aspirin (NSAID), and caffeine, approved in 1957 for pain management. The combination leverages synergistic analgesic effects: propoxyphene provides opioid-based pain relief while aspirin adds anti-inflammatory benefit and caffeine enhances alertness. It was historically used for mild-to-moderate pain across multiple indications.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100); shrinking team focus typical of legacy analgesic portfolios.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on DARVON COMPOUND offers limited career advancement; the product is in decline with no linked job openings and minimal commercial momentum. Roles are primarily defensive and focused on managing existing market share, compliance, and transition planning rather than growth or innovation.
Regulatory Affairs (compliance & legacy product management)Pharmacovigilance / Safety
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.