DARVON

LOE Approaching

propoxyphene hydrochloride

NDAORALCAPSULEPriority Review

Approved

Aug 1957

Lifecycle

LOE Approaching

Competitive Pressure

30/100

Mechanism of Action

CLINICAL PHARMACOLOGY Pharmacology Propoxyphene is a centrally acting opiate analgesic. In vitro studies demonstrated propoxyphene and the metabolite norpropoxyphene inhibit sodium channels (local anesthetic effect) with norpropoxyphene being approximately 2-fold more potent than propoxyphene and…

External Resources

DailyMed

Full prescribing information

FDA Drugs@FDA

FDA approval history

RxNorm

Drug nomenclature & identifiers