DALIRESP

LOE Approaching

roflumilast

NDAORALTABLET
Approved
Feb 2011
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

Phosphodiesterase 4 Inhibitors

Pharmacologic Class:

Phosphodiesterase 4 Inhibitor

Indications (1)

Clinical Trials (5)

NCT07077902Phase 2Recruiting

A Study for Evaluating Safety & Efficacy of Topical Roflumilast 0.3% Foam in Hidradenitis Suppurativa

Started Sep 2025
10 enrolled
Hidradenitis Suppurativa
NCT07105254Phase 2Recruiting

An Open-label Single Center, Proof of Concept Study Evaluating the Efficacy of Roflumilast Foam 0.3% in Pediatric Patients With Non-Segmental Vitiligo (NSV)

Started Aug 2025
20 enrolled
Non-segmental Vitiligo
NCT06998056Phase 2Completed

Safety Study of Roflumilast Cream 0.05% in Infants Aged 3 Months to Less Than 2 Years With Atopic Dermatitis

Started Jun 2025
101 enrolled
Atopic Dermatitis (Eczema)
NCT05028582Phase 3Completed

Topical Roflumilast to Treat Scalp and Body Psoriasis (ARRECTOR)

Started Aug 2021
432 enrolled
Scalp Psoriasis
NCT04973228Phase 3Completed

Trial of PDE4 Inhibition With Roflumilast (ARQ-154) Foam 0.3% for the Management of Seborrheic Dermatitis (STRATUM)

Started Jul 2021
457 enrolled
Seborrheic Dermatitis