CYKLOKAPRON

LOE Approaching

tranexamic acid

NDAINJECTIONINJECTABLE
Approved
Dec 1986
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
11

Mechanism of Action

derivative, which diminishes the dissolution of hemostatic fibrin by plasmin. In the presence of tranexamic acid, the lysine receptor binding sites of plasmin for fibrin are occupied, preventing binding to fibrin monomers, thus preserving and stabilizing fibrin's matrix structure. The…

Pharmacologic Class:

Antifibrinolytic Agent

Clinical Trials (5)

NCT02314988Phase 2/3Recruiting

Tranexamic Acid to Reduce Blood Loss in Spine Surgery

Started Jun 2020
252 enrolled
Spinal InjuriesSpinal Deformity
NCT03552705Phase 2Recruiting

The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients

Started Aug 2019
50 enrolled
Anterior Cruciate Ligament Reconstruction
NCT03386656Phase 3Completed

Efficacy and Safety of Topical Application of Tranexamic Acid for Saving Blood Losses in Patients Subjected to Prosthetic Knee Surgery

Started Nov 2017
150 enrolled
Osteoarthritis, Knee
NCT04986813Phase 4Completed

Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery

Started Apr 2017
NCT02535949Phase 2Completed

Tranexamic Acid Mechanisms and Pharmacokinetics in Traumatic Injury

Started Feb 2016
150 enrolled
HemorrhageShockWounds and Injuries